Protein of Epstein-Barr Virus Reveal Potential Roles for EBNA1 in Metastasis
نویسندگان
چکیده
Changes in the Nasopharyngeal Carcinoma Nuclear Proteome Induced by the EBNA1 1 Protein of Epstein-Barr Virus Reveal Potential Roles for EBNA1 in Metastasis and 2 Oxidative Stress Responses 3 Jennifer Yinuo Cao, Sheila Mansouri and Lori Frappier 4 5 Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada 6 7 * Corresponding author: 8 Department of Molecular Genetics, University of Toronto, 9 1 Kings College Circle, Toronto, Ontario Canada M5S 1A8 10 Phone: 416-946-3501 11 Fax: 416-978-6885 12 Email: [email protected] 13 14 Running Title: Effects of EBNA1 on the nuclear proteome 15 16 Abstract word count: 231 17 18 Text word count: 5656 19 20 Copyright © 2011, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved. J. Virol. doi:10.1128/JVI.05648-11 JVI Accepts, published online ahead of print on 19 October 2011
منابع مشابه
The Epstein-Barr Virus EBNA1 Protein
Epstein-Barr virus (EBV) is a widespread human herpes virus that immortalizes cells as part of its latent infection and is a causative agent in the development of several types of lymphomas and carcinomas. Replication and stable persistence of the EBV genomes in latent infection require the viral EBNA1 protein, which binds specific DNA sequences in the viral DNA. While the roles of EBNA1 were i...
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